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Journal Papers

Selected papers

NTHU BMES

  1. Bhanu Nirosha Yalamandala, Yu-Jen Chen, Ya-Hui Lin, Thi My Hue Huynh, Wen-Hsuan Chiang, Tsu-Chin Chou, Heng-Wei Liu, Chieh-Cheng Huang, Yu-Jen Lu, Chi-Shiun Chiang, Li-An Chu, Shang-Hsiu Hu*, A Self-Cascade Penetrating Brain Tumor Immunotherapy-Mediated by Near-Infrared-II Cell Membrane-Disrupting Nanoflakes via Detained Dendritic Cells, ACS Nano, 2024, 18, 18712. Journal Cover.  (SCI: 15.8)CHEMISTRY, MULTIDISCIPLINARY, N/M=4/230, Rank: 5.9%.

  2. Thi My Hue Huynh, Van-Sieu Luc, Min-Ren Chiang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Yu-Chen Liu, Chun-Yu Chuang, Chia-Chih Chang*, Shang-Hsiu Hu*, Programmed Lung Metastasis Immunotherapy via Cascade-Responsive Cell Membrane-Mimetic Copolymer-Wrapped Nanoraspberry-Mediated Elesclomol-Copper Delivery, Adv. Funct. Mater. 2024, 2401806. (SCI: 18.5) CHEMISTRY, MULTIDISCIPLINARY, N/M=10/230, Rank: 4.1%.

  3. Ting-Hsien Wu, Yu-Jen Lu, Min-Ren Chiang, Ping-Hua Chen, Yu-Sheng Lee, Ming-Yin Shen, Wen-Hsuan Chiang, Yu-Chen Liu, Chun-Yu Chuang, Hsiao-Chun Amy Lin, Shang-Hsiu Hu,*Lung Metastasis-Harnessed In-Situ Adherent Porous Organic Nanosponge-Mediated Antigen Capture for A Self-Cascaded Detained Dendritic Cells and T Cell Infiltration, Biomaterials, 2024, 305, 122443. (SCI: 12.8) MATERIALS SCIENCE, BIOMATERIALS, N/M=2/53, Rank: 2.8%

  4. Min-Ren Chiang†, Ya-Hui Lin†, Wei-Jie Zhao†, Hsiu-Ching Liu, Ru-Siou Hsu, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Lun-De Liao, Shih-Hwa Chiou, Li-An Chu*, Shang-Hsiu Hu*, In Situ Forming of Nitric Oxide and Electric Stimulus for Nerve Therapy by Wireless Chargeable Gold Yarn-Dynamos, Adv. Sci, 2023, 2303566.(†Equal contribution) (SCI: 14.3) MATERIALS SCIENCE, MULTIDISCIPLINARY, N/M=24/342, Rank: 6.9%

  5. Yi-Chieh Chan, Ya-Hui Lin, Hsiu-Ching Liua, Ru-Siou Hsu, Ming-Ren Chiang, Li-Wen Wang, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Li-An Chu*, Shang-Hsiu Hu*, In Situ Magnetoelectric Generation of Nitric Oxide and Electric Stimulus for Nerve Therapy by Wireless Chargeable Molybdenum Carbide Octahedrons, Nano Today, 2023, 51, 101935. (†Equal contribution, SCI: 13.2) MATERIALS SCIENCE, MULTIDISCIPLINARY, N/M=34/438, Rank: 7.6%.

  6. Bhanu Nirosha Yalamandala, Thi My Hue Huynh, Min-Ren Chiang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Shang-Hsiu Hu*, Catalytic Therapy and Antigen Capture-Mediated Dendritic Cells Harnessing Cancer Immunotherapies by In Situ-Forming Adhesive Nanoreservoirs, Adv. Funct. Mater. 2022, 2210644. (SCI: 18.5) CHEMISTRY, MULTIDISCIPLINARY, N/M=10/230, Rank: 4.1%.

  7. Ru-Siou Hsu, Ssu-Ju Li, Jen-Hung Fang, I-Chi Lee, Li-An Chu, Yu-Chun Lo, Yu-Jen Lu*, You-Yin Chen*, Shang-Hsiu Hu*, Wireless Charging-Mediated Angiogenesis and Nerve Repair by Adaptable Microporous Hydrogels from Conductive Building Blocks, Nat. Comm. 2022, 13, 5172. (SCI: 14.7) MULTIDISCIPLINARY SCIENCES, N/M=8/135, Rank: 6.56%

  8. Wei Cheng, Yu-Lin Su, Hao-Hsiang Hsu, Ya-Hui Lin, Li-An Chu, Wei-Chen Huang, Yu-Jen Lu, Chi-Shiun Chiang, Shang- Hsiu Hu*, Rabies Virus Glycoprotein-Mediated Transportation and T Cell Infiltration to Brain Tumor by Magnetoelectric Gold Yarnballs, ACS nano, 2022,  16, 3, 4014. (SCI: 15.8, Journal Cover) CHEMISTRY, MULTIDISCIPLINARY, N/M=4/230, Rank: 5.9%.

  9. Yu-Lin Su, Ting-Wei Yu, Wen-Hsuan Chiang, Hsin-Cheng Chiu, Chun-Hsiang Chang, Chi-Shiun Chiang, Shang-Hsiu Hu*, Hierarchically Targeted and Penetrated Delivery of Drugs to Tumors by Size-Changeable Graphene Quantum Dot Nanoaircrafts for Photolytic Therapy, Adv. Funct. Mater., 2017, 27, 1700056. (SCI: 18.5) CHEMISTRY, MULTIDISCIPLINARY, N/M=10/230, Rank: 4.1%.

  10. Chien-Ting Lin, I-Chieh Lin, Shou-Yuan Sung, Yu-Lin Su, Yu-Fen Huang, Chi-Shiun Chiang, Shang-Hsiu Hu*, Dual Targeted Photo-penetrated Delivery of Multiple Micelles/Hydrophobic Drugs by a Nanopea for Enhanced Tumor Therapy, Adv. Funct. Mater., 2016, 26, 4169.(SCI: 18.5) CHEMISTRY, MULTIDISCIPLINARY, N/M=10/230, Rank: 4.1%.

  11. Ru-Siou Hsu, Pei-Yueh Chen, Jen-Hung Fang, You-Yin Chen, Chien-Wen Chang, Yu-Jen Lu*, Shang-Hsiu Hu*, Adaptable Microporous Hydrogels of Propagating NGF-Gradient by Injectable Building Blocks for Accelerated Axonal Outgrowth, Advanced Science, 2019, 6, 1900520.  (SCI: 14.3) MATERIALS SCIENCE, MULTIDISCIPLINARY, N/M=29/438, Rank: 6.5%

  12. Yu-Lin Su, Kuan-Ting Chen, Yu-Chen Sheu, Shuo-Yuan Sung, Ru-Siou Hsu, Chi-Shiun Chiang, Shang-Hsiu Hu*, The Penetrated Delivery of Drug and Energy to Tumors by Lipo-Graphene Nanosponges for Photolytic Therapy, ACS Nano, 2016, 10, 9420. (SCI: 15.8)  CHEMISTRY, MULTIDISCIPLINARY, N/M=4/230, Rank: 5.9%.

  13. Yu-Wei Chen, Yu-Lin Su, Shang-Hsiu Hu*, San-Yuan Chen*, Functionizalized Graphene Nanocomposites for Enhancing Photothermal Therapy, Advanced Drug Delivery Reviews, 2016, 105, 190. (SCI: 15.2) PHARMACOLOGY & PHARMACY, N/M=7/354, Rank:1.84%

  14. Min-Ren Chiang, Yu-Lin Su, Chih-Yi Chang, Chein-Wen Chang, Shang-Hsiu Hu*, Lung metastasis-targeted donut-shaped nanostructures shuttled by the margination effect for the PolyDox generation-mediated penetrative delivery into deep tumors, Materials Horizons, 2020, 7, 1051. (SCI: 12.2, Journal cover)

  15. Wei-Ting Shen, Ru-Siou Hsu, Jen-Hung Fang, Pei-Fen Hu, Chi-Shiun Chiang, Shang-Hsiu Hu*, Marginative Delivery-Mediated Extracellular Leakiness and T Cell Infiltration in Lung Metastasis by Biomimetic Nano-Raspberry, Nano Letters, 2021, 3, 1375–1383. (SCI: 9.6, Journal Cover) 

  16. Jen-Hung Fang, Hao-Hsiang Hsu, Ru-Siou Hsu, Chih-Kang Peng, Yu-Jen Lu, You-Yin Chen, San-Yuan Chen*, Shang-Hsiu Hu*, 4D Printing of Stretchable Nanocookie@Conduit Hosting Biocues and Magneto-Electrical Stimulation for Neurite Sprouting, NPG Asia Materials, 2020, 12, 61. (SCI: 8.6)

  17. Shou-Yuan Sung, Yu-Lin Su, Wei Cheng, Pei-Feng Hu, Chi-Shiun Chiang, Wen-Ting Chen, Shang- Hsiu Hu*, Graphene Quantum Dots-Mediated Theranostic Penetrative Delivery of Drug and Photolytics in Deep Tumors by Targeted Biomimetic Nanosponges, Nano Letters, 2019, 19, 69. (SCI: 9.6) 

  18. Yu-Lin Su, Li-Wen Kuo, Chia-Hsien Hsu, Chi-Shiun Chiang, Yu-Jen Lu, Shing-Jyh Chang, Shang-Hsiu Hu*, Rabies virus glycoprotein-amplified hierarchical targeted hybrids capable of magneto-electric penetration delivery to orthotopic brain tumor, J. Control. Release, 2020, 321, 159. (SCI: 10.5) PHARMACOLOGY & PHARMACY, N/M=12/354, Rank: 4.2 %

NTHU

BMES

2022-2024

  1. Bhanu Nirosha Yalamandala, Yu-Jen Chen, Ya-Hui Lin, Thi My Hue Huynh, Wen-Hsuan Chiang, Tsu-Chin Chou, Heng-Wei Liu, Chieh-Cheng Huang, Yu-Jen Lu, Chi-Shiun Chiang, Li-An Chu, Shang-Hsiu Hu*, A Self-Cascade Penetrating Brain Tumor Immunotherapy-Mediated by Near-Infrared-II Cell Membrane-Disrupting Nanoflakes via Detained Dendritic Cells, ACS Nano, 2024, 18, 18712. (SCI: 15.8)CHEMISTRY, MULTIDISCIPLINARY, N/M=4/230, Rank: 5.9%.

  2. Thi My Hue Huynh, Van-Sieu Luc, Min-Ren Chiang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Yu-Chen Liu, Chun-Yu Chuang, Chia-Chih Chang*, Shang-Hsiu Hu*, Programmed Lung Metastasis Immunotherapy via Cascade-Responsive Cell Membrane-Mimetic Copolymer-Wrapped Nanoraspberry-Mediated Elesclomol-Copper Delivery, Adv. Funct. Mater. 2024, 2401806(SCI: 18.5) CHEMISTRY, MULTIDISCIPLINARY, N/M=10/230, Rank: 4.1%.

  3. Ting-Hsien Wu, Yu-Jen Lu, Min-Ren Chiang, Ping-Hua Chen, Yu-Sheng Lee, Ming-Yin Shen, Wen-Hsuan Chiang, Yu-Chen Liu, Chun-Yu Chuang, Hsiao-Chun Amy Lin, Shang-Hsiu Hu,*Lung Metastasis-Harnessed In-Situ Adherent Porous Organic Nanosponge-Mediated Antigen Capture for A Self-Cascaded Detained Dendritic Cells and T Cell Infiltration, Biomaterials, 2024, 305, 122443. (SCI: 12.8) MATERIALS SCIENCE, BIOMATERIALS, N/M=2/53, Rank: 2.8%

  4. Shih-Jie Chou, Yi-Ping Yang, Min-Ren Chiang, Chih-Ying Chen, Henkie Isahwan Ahmad Mulyadi Lai, Yi-Ying Lin, You-Ren Wu, I-Chieh Wang, Aliaksandr A. Yarmishyn, Guang-Yuh Chiou, Tai-Chi Lin, Der-Kuang Hwang, Shih-Jen Chen, Yueh Chien*, Shang-Hsiu Hu*, Shih-Hwa Chiou*, Ophthalmic Tethered Gold Yarnball-Mediated Retained Drug Delivery for Eye-fundus Disease Treatment, Small Science, 2024, accepted. (SCI: 11.1)  MATERIALS SCIENCE, MULTIDISCIPLINARY, N/M=44/438, Rank: 9.9%

  5. Yu-Hsin Chen, I-Ju Liu, Tzu-Chen Lin, Min-Chen Tsai, Shang-Hsiu Hu, Tsai-Ching Hsu, Yi-Ting Wu, Bor-Show Tzang, Wen-Hsuan Chiang, PEGylated chitosan-coated nanophotosensitizers for effective cancer treatment by photothermal-photodynamic therapy combined with glutathione depletion,  International Journal of Biological Macromolecules, 2024, 266, 131359. (SCI: 7.7)

  6. Nien-Tzu Yeh,  Tzu-Chen Lin, I-Ju Liu, Shang-Hsiu Hu, Tsai-Ching Hsu, Hao-Yang Chin, Bor-Show Tzang, 
    Wen-Hsuan Chiang, 
    Hyaluronic acid-covered ferric ion-rich nanobullets with high zoledronic acid payload for breast tumor-targeted chemo/chemodynamic therapy, International Journal of Biological Macromolecules, 2024, 135271. (
    SCI: 7.7)

  7. Lu, Y.-J.; Vayalakkara, R.K.; Dash, B.S.; Hu, S.-H.; Premji, T.P.; Wu, C.-Y.; Shen, Y.-J.; Chen, J.-P. Immunomodulatory R848-Loaded Anti-PD-L1-Conjugated Reduced Graphene Oxide Quantum Dots for Photothermal Immunotherapy of Glioblastoma. Pharmaceutics 2024, 16, 1064.

  8. Yu-Ling Liu, Tzu-Hao Wang, Nien-Tzu Yeh, Wei-Jen Huang, B. S. Tzang, I-Ting Wu, Hao-Yang Chin, Shang-Hsiu Hu,   Tsai-Ching Hsu, Wen-Hsuan Chiang, Tumor-activated targetable photothermal-chemotherapy of IR780/zoledronic acid-containing hybrid polymeric nanoassemblies with folate modification to treat aggressive breast cancer, Nanoscale, 2024, Accepted. 

  9. Ya-Hui Lin, Li-Wen Wang, Yen-Hui Chen, Yi-Chieh Chan, Shang-Hsiu Hu, Sheng-Yan Wu, Chi-Shiun Chiang, Guan-Jie Huang, Shang-Da Yang, Shi-Wei Chu, Kuo-Chuan Wang, Chin-Hsien Lin, Pei-Hsin Huang, Hwai-Jong Cheng, Bi-Chang Chen, Li-An Chu, Revealing intact neuronal circuitry in centimeter-sized formalin-fixed paraffin-embedded brain, eLife, 2024, 13:RP93212.

  10. Min-Ren Chiang†, Ya-Hui Lin†, Wei-Jie Zhao†, Hsiu-Ching Liu, Ru-Siou Hsu, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Lun-De Liao, Shih-Hwa Chiou, Li-An Chu*, Shang-Hsiu Hu*, In Situ Forming of Nitric Oxide and Electric Stimulus for Nerve Therapy by Wireless Chargeable Gold Yarn-Dynamos, Adv. Sci, 2023, 2303566.(†Equal contribution(SCI: 14.3) MATERIALS SCIENCE, MULTIDISCIPLINARY, N/M=29/438, Rank: 6.5%

  11. Hsiu-Ching Liu, Chu-Han Huang, Min-Ren Chiang, Ru-Siou Hsu, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Lun-De Liao, Shih-Hwa Chiou, Zhong-Hong Lin, Shang-Hsiu Hu*, Sustained Release of Nitric Oxide-Mediated Angiogenesis and Nerve Repair by Mussel-Inspired Adaptable Microreservoirs for Brain Traumatic Injury Therapy, Adv. Health. Mater., 2023, 2302315. (SCI: 10.0) MATERIALS SCIENCE, BIOMATERIALS, N/M=3/53, Rank: 4.7 %

  12. Yi-Chieh Chan, Ya-Hui Lin, Hsiu-Ching Liua, Ru-Siou Hsu, Ming-Ren Chiang, Li-Wen Wang, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Li-An Chu*, Shang-Hsiu Hu*, In Situ Magnetoelectric Generation of Nitric Oxide and Electric Stimulus for Nerve Therapy by Wireless Chargeable Molybdenum Carbide Octahedrons, Nano Today, 2023, 51, 101935. (†Equal contribution, SCI: 13.2) MATERIALS SCIENCE, MULTIDISCIPLINARY, N/M=34/438, Rank: 7.6%.

  13. Min-Ren Chiang, Wei-Ting Shen, Pin-Xuan Huang, Kang-Li Wang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Yu-Chen Liu,  Shing-Jyh Chang, Shang-Hsiu Hu*, Programmed T Cells Infiltration into Lung Metastases with Harnessing Dendritic Cells in Cancer Immunotherapies by Catalytic Antigen-Capture Sponges, J. Control. Release, 2023, 360, 260-273.  (SCI: 10.5) PHARMACOLOGY & PHARMACY, N/M=12/354, Rank: 4.2 %

  14. Thi My Hue Huynh, Bhanu Nirosha Yalamandala, Min-Ren Chiang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Lun-De Liao, Yu-Chen Liu, Shang-Hsiu Hu*, Programmed antigen capture-harnessed dendritic cells by margination-hitchhiking lung delivery, J. Control. Release, 2023, 358, 718-728. (SCI: 10.5) PHARMACOLOGY & PHARMACY, N/M=12/354, Rank: 4.2 %

  15. Bhanu Nirosha Yalamandala, Thi My Hue Huynh, Min-Ren Chiang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Shang-Hsiu Hu*, Catalytic Therapy and Antigen Capture-Mediated Dendritic Cells Harnessing Cancer Immunotherapies by In Situ-Forming Adhesive Nanoreservoirs, Adv. Funct. Mater. 2022, 2210644. 

  16. Ru-Siou Hsu, Ssu-Ju Li, Jen-Hung Fang, I-Chi Lee, Li-An Chu, Yu-Chun Lo, Yu-Jen Lu*, You-Yin Chen*, Shang-Hsiu Hu*, Wireless Charging-Mediated Angiogenesis and Nerve Repair by Adaptable Microporous Hydrogels from Conductive Building Blocks, Nat. Comm. 2022, 13, 5172.

  17. Wei Cheng, Yu-Lin Su, Hao-Hsiang Hsu, Ya-Hui Lin, Li-An Chu, Wei-Chen Huang, Yu-Jen Lu, Chi-Shiun Chiang, Shang- Hsiu Hu*, Rabies Virus Glycoprotein-Mediated Transportation and T Cell Infiltration to Brain Tumor by Magnetoelectric Gold Yarnballs, ACS nano, 2022, 16, 3, 4014.  (Journal Cover) 

  18. Bhanu Nirosha Yalamandala, Pin-Hua Chen, Thrinayan Moorthy, Thi My Hue Huynh, Wen-Hsuan Chiang, Shang-Hsiu Hu*, Programmed Catalytic Therapy-Mediated ROS Generation and T-cell 
    Infiltration in Lung Metastasis by Dual Metal Organic Framework (MOF) Nanoagnets, Pharmaceutics, 2022, 14, 527.  
    (Journal Cover) 

  19. Bo-Wei Chen, Shadie Hatamie, Hsin-Cheng Chiu, Zung-Hang Wei, Shang-Hsiu Hu*, and Da-Jeng Yao*, Shape-Mediated Magnetocrystalline Anisotropy and Relaxation Controls by Cobalt Ferrite Core-Shell Heterostructures for Magnetothermal Penetration Delivery,  Adv. Mater. Interfaces 2022, 2200022. (Journal Cover) 

  20. Ming-Hung Hsieh, Tzu-Hao Wang, Shang-Hsiu Hu, Tsai-Ching Hsu, Jia-LeYow, Bor-Show Tzang, Wen-Hsuan Chiang, Tumor site-specific PEG detachment and active tumor homing of therapeutic PEGylated chitosan/folate-decorated polydopamine nanoparticles to augment antitumor efficacy of photothermal/chemo combination therapy, Chemical Engineering Journal, 2022, 446, 137243.

  21. Yu-Ning Hung, Yu-Ling Liu, Ya-Hsuan Chou, Shang-Hsiu Hu, Bill Cheng, Wen-Hsuan Chiang,
    Promoted cellular uptake and intracellular cargo release of ICG/DOX-carrying hybrid polymeric nanoassemblies upon acidity-activated PEG detachment to enhance cancer photothermal/chemo combination therapy, European Polymer Journal, 2022, 163, 110944.

  22. Chieh-Wei Chung, Bo-Wen Liao, Shu-Wei Huang, Show-Jen Chiou, Cheng-Han Chang, Sheng-Ju Lin, Bo-Hao Chen, Wei-Ling Liu, Shang-Hsiu Hu, Yu-Chun Chuang, Chia-Her Lin, I-Jui Hsu, Chao-Min Cheng, Chieh-Cheng Huang, Tsai-Te Lu, Magnetic Responsive Release of Nitric Oxide from an MOF-Derived Fe3O4@PLGA Microsphere for the Treatment of Bacteria-Infected Cutaneous Wound, ACS Appl. Mater. Interfaces 2022, 14, 5, 6343–6357.

2021

  1. Fu-Erh Chan, Huei-Min Syu, Te-Yi Wang, Zheng-Ting Tang, Chih-Ning Huang, Jyh-Fu Lee, Thierry Burnouf, Shang-Hsiu Hu, Po-Chun Chen, Wei-Chen Huang, Iridium Oxide Nanoparticle–Protein Corona Neural Interfaces with Enhanced Electroactivity and Bioactivity Enable Electrically Manipulatable Physical and Chemical Neuronal Activation, Adv. Mater. Interfaces 2021, 8, 2100694. (Journal Cover) 

  2. Bhanu Nirosha Yalamandala, Wei-Ting Shen, Sheng-Hao Min, Wen-Hsuan Chiang, Shing-Jyh Chang, Shang-Hsiu Hu*, Advances in Functional Metal-Organic Frameworks-Based On-Demand Drug Delivery Systems for Tumor Therapeutics, Advanced NanoBiomed Research, 2021, 2100014. (Invited review, Journal Cover) 

  3. Wei-Ting Shen, Ru-Siou Hsu, Jen-Hung Fang, Pei-Fen Hu, Chi-Shiun Chiang, Shang-Hsiu Hu*, Marginative Delivery-Mediated Extracellular Leakiness and T Cell Infiltration in Lung Metastasis by Biomimetic Nano-Raspberry, Nano Letters, 2021, 21, 1375–1383.  (Journal Cover)

  4. Min-Ren Chiang, Yu-Lin Su, Chih-Yi Chang, Chein-Wen Chang, Shang-Hsiu Hu*, Lung metastasis-targeted donut-shaped nanostructures shuttled by the margination effect for the PolyDox generation-mediated penetrative delivery into deep tumors, Materials Horizons, 2020, 7, 1051. (Journal Cover)

  5. Jen-Hung Fang, Hao-Hsiang Hsu, Ru-Siou Hsu, Chih-Kang Peng, Yu-Jen Lu, You-Yin Chen, San-Yuan Chen*, Shang-Hsiu Hu*, 4D Printing of Stretchable Nanocookie@Conduit Hosting Biocues and Magneto-Electrical Stimulation for Neurite Sprouting, NPG Asia Materials, 2020,12, 61.  

  6. Ru-Siou Hsu, Jen-Hung Fang, Wei-Ting Shen, Yu-Chen Sheu, Cheng-Kuan Su, Wen-Hsuan Chiang, Shang-Hsiu Hu*, DNA-Architected Nano-Raspberry Depot-Mediated On-Demand Programmable Refilling and Release Drug Delivery, Nanoscale, 2020,12, 11153.

  7. Yu-Lin Su, Li-Wen Kuo, Chia-Hsien Hsu, Chi-Shiun Chiang, Yu-Jen Lu, Shing-Jyh Chang, Shang-Hsiu Hu*, Rabies virus glycoprotein-amplified hierarchical targeted hybrids capable of magneto-electric penetration delivery to orthotopic brain tumor, J. Control. Release, 2020, 321, 159. 

  8. Jen-Hung Fang, Che-Hau Liu, Ru-Siou Hsu, Yin-Yu Chen, Wen-Hsuan Chiang, Hui-Min David Wang, Shang-Hsiu Hu*, Transdermal Composite Microneedle Composed of Mesoporous Iron Oxide Nanoraspberry and PVA for Androgenetic Alopecia Treatment, Polymers, 2020, 12, 1392. (Feature Paper; Editor's Choice Article;Invited paper)

  9. Min-Cong Xiao, Ya-Hsuan Chou, Yu-Ning Hung, Shang-Hsiu Hu, Wen-Hsuan Chiang*, Hybrid polymeric nanoparticles with high zoledronic acid payload and proton sponge-triggered rapid drug release for anticancer applications, Materials Science & Engineering C, 2020, 116, 111277. 

  10. Hsing-Yu Haung, Yi-Chen Wang, Ying-Chen Cheng, Wenyi Kang, Shang-Hsiu Hu, Dengyong Liu, Chaogeng Xiao, Hui-Min D. Wang*,  A novel oral astaxanthin nanoemulsion from Haematococcus pluvialis induces apoptosis in lung metastatic melanoma", Oxidative Medicine and Cellular Longevity, 2020, Volume 2020, Article ID 2647670. 

  11. Ru-Siou Hsu, Pei-Yueh Chen, Jen-Hung Fang, You-Yin Chen, Chien-Wen Chang, Yu-Jen Lu*, Shang-Hsiu Hu*, Adaptable Microporous Hydrogels of Propagating NGF-Gradient by Injectable Building Blocks for Accelerated Axonal Outgrowth, Advanced Science, 2019, 6, 1900520. 

  12. Shou-Yuan Sung, Yu-Lin Su, Wei Cheng, Pei-Feng Hu, Chi-Shiun Chiang, Wen-Ting Chen, Shang- Hsiu Hu*, Graphene Quantum Dots-Mediated Theranostic Penetrative Delivery of Drug and Photolytics in Deep Tumors by Targeted Biomimetic Nanosponges, Nano Letters, 2019, 19, 69.

  13. Yu-Lin Su, Shang-Hsiu Hu*, Functional Nanoparticles for Tumor Penetration of Therapeutics. Pharmaceutics, 2018, 10, 193. (Invited review) 

  14. Hoon Choi, Ting Liu, Hui Qiao, Ann-MarieChacko, Shang-Hsiu Hu, San-Yuan Chen, Rong Zhou, I-Wei Chen, Biomimetic nano-surfactant stabilizes sub-50 nanometer phospholipid particles enabling high paclitaxel payload and deep tumor penetration, Biomaterials, 2018, 181, 240. 

  15. Yu-Lin Su, Ting-Wei Yu, Wen-Hsuan Chiang, Hsin-Cheng Chiu, Chun-Hsiang Chang, Chi-Shiun Chiang, Shang-Hsiu Hu*, Hierarchically Targeted and Penetrated Delivery of Drugs to Tumors by Size-Changeable Graphene Quantum Dot Nanoaircrafts for Photolytic Therapy, Adv. Funct. Mater., 2017, 27, 1700056. 

  16. Yu-Lin Su, Kuan-Ting Chen, Yu-Chen Sheu, Shuo-Yuan Sung, Ru-Siou Hsu, Chi-Shiun Chiang, Shang-Hsiu Hu*, The Penetrated Delivery of Drug and Energy to Tumors by Lipo-Graphene Nanosponges for Photolytic Therapy, ACS Nano, 2016, 10, 9420. 

  17. Yu-Wei Chen, Yu-Lin Su, Shang-Hsiu Hu*, San-Yuan Chen*, Functionizalized Graphene Nanocomposites for Enhancing Photothermal Therapy, Advanced Drug Delivery Reviews, 2016, 105, 190. 

  18. I-Chieh Lin, Jen-Hung Fang, Chien-Ting Lin, Shou-Yuan Sung, Yu-Lin Su, Shang-Hsiu Hu*, Enhanced Targeted Delivery of Cyclodextrin-based Supermolecules by Core-Shell Nanocapsules for Magneto-thermal Chemotherapy, Macromolecular Bioscience, 2016, 16, 1273. (Journal Cover)

  19. Chien-Ting Lin, I-Chieh Lin, Shou-Yuan Sung, Yu-Lin Su, Yu-Fen Huang, Chi-Shiun Chiang, Shang-Hsiu Hu*, Dual Targeted Photo-penetrated Delivery of Multiple Micelles/Hydrophobic Drugs by a Nanopea for Enhanced Tumor Therapy, Adv. Funct. Mater., 2016, 26, 4169. (IF=15.621)

  20. Srivardhan Reddy Gayam, Parthiban Venkatesan, Yi-Ming Sung, Shou-Yuan Sung, Shang-Hsiu Hu, Hsin-Yun Hsu, Shu-Pao Wu, NAD(P)H: quinone oxidoreductase 1 (NQO1) enzyme responsive nanocarrier based on mesoporous silica nanoparticles for tumor targeted drug delivery in vitro and in vivo. Nanoscale, 2016, in press. 

  21. Ting-Wei Yu, I.-Lin Lu, Wen-Chia Huang, Shang-Hsiu Hu, Chia-Chian Hung, Wen-Hsuan Chiang, Hsin-Cheng Chiu, Acidity-triggered surface charge neutralization and aggregation of functionalized nanoparticles for promoted tumor uptake,  RSC Adv., 2016, 6, 36293. 

  22. Jen-Hung Fang, Tsung-Lang Chiu, Wei-Chen Huang, Yen-Ho Lai, Shang-Hsiu Hu, You-Yin Chen, and San-Yuan Chen, Dual-Targeting Lactoferrin-Conjugated Polymerized Magnetic Polydiacetylene-Assembled Nanocarriers with Self-Responsive Fluorescence/Magnetic Resonance Imaging for In Vivo Brain Tumor Therapy, Adv. Healthcare Mater., 2016, 5, 688.

  23. Yu-Lin Su, Jen-Hung Fang, Chia-Ying Liao, Chein-Ting Lin, Yun-Ting Li, Shang-Hsiu Hu*, Targeted Mesoporous Iron Oxide Nanoparticles-Encapsulated Perfluorohexane and a Hydrophobic Drug for Deep Tumor Penetration and Therapy, Theranostics, 2015, 5, 1233.  (Journal Cover)

  24. Jen-Hung Fang, Yun-Ting Li, Wen-Hsuan Chiang, Shang-Hsiu Hu*, Magnetoresponsive Virus-Mimetic Nanocapsules with Dual Heat-Triggered Sequential-Infected Multiple Drug-Delivery Approach for Combinatorial Tumor Therapy, Small, 2015, 11, 2417. 

  25. Chia-Wei Su, Chih-Sheng Chiang, Wei-Ming Li, Shang-Hsiu Hu, San-Yuan Chen, Multifunctional nanocarriers for simultaneous encapsulation of hydrophobic and hydrophilic drugs in cancer treatment, Nanomedicine, 2014, 9, 1499-1515.(Invited review)

  26. Shang-Hsiu Hu, Ren-Hong Fang, Yu-Wei Chen, Bang-Jie Liao, I-Wei Chen, San-Yuan Chen, Photo-Responsive Protein-Graphene-Protein Hybrid Capsules with Dual Targeted Heat-Triggered Drug Delivery Approach for Enhanced Tumor Therapy, Adv. Funct. Mater., 2014, 24, 4144. 

  27.   Jen-Hung Fang, Yen-Ho Lai, Tsung-Lang Chiu, You-Yin Chen, Shang-Hsiu Hu*, San-Yuan Chen*, Magnetic Core/Shell Nanocapsules with Dual Targeting Capabilities and Co-Delivery of Multiple Drugs to Treat Brain Gliomas, Adv. Healthcare Mater. 2014, 3, 1250.

  28.  Shang-Hsiu Hu, Tsung-Ying Hsieh, Chin-Sheng Chiang, Po-Jung Chen, You-Yin Chen, Tsung-Lang Chiu, San-Yuan Chen, Surfactant-Free, Lipo-Polymersomes Stabilized by Iron Oxide Nanoparticles/Polymer Interlayer for Synergistically Targeted and Magnetically Guided Gene Delivery, Adv. Healthcare Mater. 2014, 3, 273.

  29.  Heng-Wen Liu, Wei-Chen Huang, Chih-Sheng Chiang, Shang-Hsiu Hu, Chia-Hsin Liao, You-Yin Chen, San-Yuan Chen, Arrayed rGOSH/PMASH Microcapsule Platform Integrating Surface Topography, Chemical Cues, and Electrical Stimulation for Three-Dimensional Neuron-Like Cell Growth and Neurite Sprouting, Adv. Funct. Mater., 2014, 24, 3715. 

  30.   Yu-Wei Chen, Po-Jung Chen, Shang-Hsiu Hu, I-Wei Chen, San-Yuan Chen, NIR-Triggered Synergic Photo-chemothermal Therapy Delivered by Reduced Graphene Oxide/Carbon/Mesoporous Silica Nanocookies, Adv. Funct. Mater., 2014, 24, 451-459.

  31.   Chih-Sheng Chiang, Shang-Hsiu Hu, Bang-Jie Liao, Yuan-Ching Chang, San-Yuan Chen, Enhancement of cancer therapy efficacy by trastuzumab-conjugated and pH-sensitive nanocapsules with the simultaneous encapsulation of hydrophilic and hydrophobic compounds, Nanomedicine: Nanotechnology, Biology, and Medicine, 2014, 10, 99-107.

  32.   Hsin-Yang Huang, Shang-Hsiu Hu, Shih-Ya Hung, Chih-Sheng Chiang, Hao-Li Liu, Tsung-Lang Chiu, Hsin-Yi Lai, You-Yin Chen, San-Yuan Chen, SPIO nanoparticle-stabilized PAA-F127 thermosensitive nanobubbles with MR/US dual-modality imaging and HIFU-triggered drug release formagnetically guided in vivo tumor therapy, Journal of Controlled Release, 2013, 172, 118–127.

NCTU MSE

2010-2013

UW BioE

2019-2010

NCTU MSE

2006-2010

  1. Shang-Hsiu Hu, Bang-Jie Liao, Chin-Sheng Chiang, Po-Jung Chen, I-Wei Chen, and San-Yuan Chen, Core-shell Nanocapsules Stabilized by Single-Component Polymer and Nanoparticles for Magneto-Chemotherapy-Hyperthermia with Multiple Drugs, Adv. Mater., 2012, 24, 3627. 

  2. Heng-Wen Liu, Shang-Hsiu Hu, Yu-Wei Chen and San-Yuan Chen, Characterization and drug release behavior of highly responsive chip-like electrically modulated reduced graphene oxide–poly(vinyl alcohol) membranes, J. Mater. Chem., 2012, 22, 17311.

  3. Shang-Hsiu Hu, San-Yuan Chen, and Xiaohu Gao, Multifunctional nanocapsules for simultaneous encapsulation of hydrophilic and hydrophobic compounds and on-demand release, ACS Nano, 2012, 6, 2558. 

  4. Shang-Hsiu Hu, Yu-Wei Chen, Wen-Ting Hung, I-Wei Chen, and San-Yuan Chen, Quantum-Dot-Tagged Reduced Graphene Oxide Nanocomposites for Bright Fluorescence Bioimaging and Photothermal Therapy Monitored In Situ, Adv. Mater., 2012, 24, 1748.

  5. Hsin-Yang Huang, Shang-Hsiu Hu, Chih-Shang Chian, San-Yuan Chen, Hsin-Yi Lai and You-Yin Chen, Self-assembling PVA-F127 thermosensitive nanocarriers with highly sensitive magnetically-triggered drug release for epilepsy therapy in vivo, J. Mater. Chem., 2012, 22, 8566.

  6. Po-Jung Chen, Shang-Hsiu Hu, Wen-Ting Hung, San-Yuan Chen and Dean-Mo Liu, Geometrical confinement of quantum dots in porous nanobeads with ultraefficient fluorescence for cell-specific targeting and bioimaging J. Mater. Chem., 2012, 22, 9568.

  7. Shang-Hsiu Hu, You-Yin Chen, Ta-Chung Liu, Tsan-Hua Tung, Dean-Mo Liu, and San-Yuan Chen, Remotely nano-rupturable yolk/shell capsules for magnetically- triggered drug release, Chem. Commun., 2011, 47, 1776.

  8. Po-Jung Chen, Shang-Hsiu Hu, Chi-Sheng Hsiao, You-Yin Chen, Dean-Mo Liu and San-Yuan Chen, Multifunctional magnetically removable nanogated lids of Fe3O4–capped mesoporous silica nanoparticles for intracellular controlled release and MR imaging, J. Mater. Chem., 2011, 21, 2535.

  9. Wei-Lin Tung, Shang-Hsiu Hu, Dean-Mo Liu, Synthesis of nanocarriers with remote magnetic drug release control and enhanced drug delivery for intracellular targeting of cancer cells, Acta Biomater., 2011, Article in press.

  10. Shang-Hsiu Hu, and Xiaohu Gao, "Nanocomposites with Spatially Separated Functionalities for Combined Imaging and Magnetolytic Therapy", J. Am. Chem. Soc., 2010, 132, 7234-7237. 

  11. Shang-Hsiu Hu, and Xiaohu Gao, "Stable Encapsulation of QD Barcodes with Silica Shells", Adv. Func. Mat., 2010, 20, 3721. 

  12. Kuan-Ting Kuo, Shang-Hsiu Hu, Dean-Mo Liu, and San-Yuan Chen. Magnetically-induced Synthesis of Highly-Crystalline Ternary Semiconductor Chalcopyrite Nanocrystals via a Magnetic Doping at Ambient Conditions, Journal of Materials Chemistry, 2010, 20, 1744-1750. 

  13. Shang-Hsiu Hu, Kuan-Ting Kuo, Wei-Lin Tung, Dean-Mo Liu, and San-Yuan Chen. Synthesis of Drug Delivery Nano-device capable of Imagining, Targeting, and Self-Monitoring of Drug Release in Cancerous Cells, Adv. Func. Mat., 2009, 19, 3396. 

  14. Wei-Chen Huang, Shang-Hsiu Hu, Kun-Ho Liu, San-Yuan Chen and Dean-Mo Liu. A Flexible Drug Delivery Chip for Magnetically-Controlled Release of Anti-Epileptic Drug, Journal of Controlled Drug Release, 2009, 139, 221-228.

  15. Ting-Yu Liu, Shang-Hsiu Hu, Dean-Mo Liu, San-Yuan Chen, and I-Wei Chen, Biomedical Nanoparticle Carriers with Combined Thermal and Magnetic Responses, NanoToday, 2009, 4, 52-69 ( invited review). 
    Shang-Hsiu Hu, Ting-Yu Liu, Hsin-Yang Huang, Dean-Mo Liu, and San-Yuan Chen, Stimuli-Responsive Controlled Drug Release from Magnetic-Sensitive Silica Nanospheres, J. Nanosci. Nanotechnol., 2009, 9, 866-870.

  16. Shang-Hsiu Hu, Chia-Hui Tsai, Chen-Fu Liao, Dean-Mo Liu and San-Yuan Chen, Controlled Rupture of Magnetic Polyelectrolyte Microcapsules for Drug Delivery, Langmuir, 2008, 24, 11811–11818. 

  17. Shang-Hsiu Hu, Wei-Lin Tung, Chen-Fu Liao, Dean-Mo Liu and San-Yuan Chen, Surfactant-free, Self-Assemble PVA-Iron Oxide /Silica Core-Shell Nanocarriers for High-Sensitive Magnetically Controlled Drug Release and Ultra-high Cancer Cell Uptake Efficiency, Adv. Func. Mat., 2008, 18, 2946-2955.

  18. Shang-Hsiu Hu, San-Yuan Chen, Chi-Sheng Hsiao and Dean-Mo Liu, “Core/Single-Crystal-Shell Nanospheres for Controlled Drug Release via a Magnetically Triggered Rupturing Mechanism”, Adv. Mat., 2008, 20, 2690-2695.

  19. Ting-Yu Liu, Shang-Hsiu Hu, Kun-Ho Liu, Dean-Mo Liu and San-Yuan Chen, Instantaneous Drug Delivery of Magnetic/Thermal Sensitive Nanospheres by a High Frequency Magnetic Field, Langmuir, 2008, 24, 13306-13311.

  20. Ting-Yu Liu, Shang-Hsiu Hu, Kun-Ho Liu, Dean-Mo Liu and San-Yuan Chen, “Study on controlled drug permeation of magnetic-sensitive ferrogels: Effect of Fe3O4 and PVA ”, Journal of Controlled Drug Release, 2008, 126, 228-236. 

  21. Shang-Hsiu Hu, Ting-Yu Liu, Hsin-Yang Huang, Dean-Mo Liu and San-Yuan Chen, “Magnetic-Sensitive Silica Nanospheres for Controlled Drug Release”, Langmuir, 2008, 23, 239.

  22. Ting-Yu Liu, Li-Ying Huang, Shang-Hsiu Hu, Ming-Chien Yang and San-Yuan Chen, Core-shell magnetic nanoparticles of heparin conjugate as recycling anticoagulants, J. Biomed. Nanotechnol., 2007, 7, 353.

  23. Shang-Hsiu Hu, Ting-Yu Liu, Dean-Mo Liu and San-Yuan Chen, “Controlled Pulsatile Drug Release from a Ferrogel by a High-Frequency Magnetic Field”, Macromolecules, 2007, 40(19), 6786-6788. 

  24. Shang-Hsiu Hu, Ting-Yu Liu, Dean-Mo Liu and San-Yuan Chen, “Nano- Ferrosponges For Controlled Drug Release”, Journal of Controlled Drug Release, 2007, 121 (3), 181-189.

  25. Shang-Hsiu Hu, Ting-Yu Liu, Chia-Hui Tsai, Dean-Mo Liu and San-Yuan Chen, “Preparation and Characterization of magnetic ferroscaffolds for tissue engineering”, Journal of Magnetism and Magnetic Materials, 2007, 310(2), 2871-2873. 

  26. Ting-Yu Liu, Shang-Hsiu Hu, Sheng-Hsiang Hu, Szu-Ping Tsai and San-Yuan Chen, “Preparation and characterization of thermal-sensitive ferrofluids for drug delivery application ”, Journal of Magnetism and Magnetic Materials, 2007, 310 (2), 2850-2852. 

  27. Ting-Yu Liu, Shang-Hsiu Hu, Tse-Ying Liu, Dean-Mo Liu and San-Yuan Chen,” Magnetic-sensitive behavior of intelligent ferrogels for controlled release of drug,” Langmuir, 2006; 22(14); 5974-5978.

  28. Ting-Yu Liu, Hung-Chou Liao, Chin-Ching Lin, Shang-Hsiu Hu, and San-Yuan Chen, ” Bio-functional ZnO nanorods arrays grown on flexible substrates,” Langmuir; 2006; 22(13); 5804-5809. 

  29. Ting-Yu Liu, Shang-Hsiu Hu, Kun-Ho Liu, Dean-Mo Liu, San-Yuan Chen, “Preparation and characterization of smart magnetic hydrogels and its use for drug release,” Journal of Magnetism and Magnetic Materials, 304, 2006, e397-e399.

  30. Jiang-Jen Lin, Shi-Min Chen, Shang-Hsiu Hu, ” Poly(oxyethylene) diamine- Derived Hydrophilic Copolymers for Emulsifying Diglycidylether of Bisphenol-A, ”Journal of Applied Polymer Science, Vol. 94, 1797–1802 (2004).

Patents

  1. K5P107033-TW (107B0193-I1)「含硼參雜石墨烯量子點的奈米複合物及其應用」,蘇昱璘、胡尚秀。美國、中華民國,2021 獲證。

  2. K5P107042-TW「可注射型自組裝微球凝膠、其用途及可注射型自組裝微球凝膠的製備方法」,許如秀、胡尚秀,2018,美國、中華民國。Pending 

  3. K5P107033-US (107F0260-IE)「仿狂犬病毒之樹狀高分子/石墨烯量子點奈米載體應用於腦瘤穿透治療」,美國專利 申請號:16/239,963,申請日:2019/01/04。2020/12/09 美國獲證。證 書 號:US 10,894,020

  4. 專利權起訖日:2021年1月19日起至2039年1月4日止

  5. K5P104004(103F0683-IE)「用於藥物傳遞的蛋白質納米磁性殼核膠囊及其應用」大陸專利獲證, 2019年 03月 13日。

  6.  K5P107042-US,  INJECTABLE AND SHEARING-THINNING MICROBEADS GEL, USE THEREOF,  AND METHOD FOR PREPARING THE SAME, 2019. 

Book Chapter

  1. l San-Yuan Chen, Shang-Hsiu Hu, Ting-Yu Liu, “Magnetic-responsive Nanoparticles for Drug Delivery”, RSC Book Smart Materials for Drug Delivery, RSC Publicaiton/Wiley, 2012.

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